1)      Zoster lesions in multiple dermatomes – immunocompromise

2)      Zoster lesions which are hemorrhagic, gangrenous, bullous (sever heres zoster ? underlying immunosuppression)

3)      Ophthalmic zoster involving the tip of the nose (risk of zoster keratoconjunctivitis, ophthalmologist referral)

4)      Zoster not responding to acyclovir (? HIV infection)